When created give the executing user Read/Create/Change permissions on the root folders ".\systemprofile" to allow the running user to access the directory's tree.
As these settings are bound to the user and not the local machine.Īfter that, it is essential (strange as it seems) to create two new folders called "Desktop" beneath "C:\Windows\System32\config\systemprofile" and also "C:\Windows\SysWOW64\config\systemprofile". Also you might need to set some Trust Center settings to allow for example working with old XLS 4.0 Formats, and so on. I suggest you to log-in to Windows with the service user and run Excel one time to have a user profile set up and Excel registered to that user.
I adapted that from the following article: Answer (1 of 2): It can be possible in one scenario or i can say 2 if you have performed office repair online then it starts takes uninstall and reinstall of office package online in other case if any new version or new update was pushed through SCCM over your machine it takes self uninstallation. When you are using Microsoft Excel 2016 on a Windows Server 2016 Machine, you need to run " C:\Program Files (x86)\Microsoft Office\root\Office16\Excel.exe -REGSERVER" with admin privileges.
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